pancreatic: Celgene determined to continue fight for patient access to its metastatic pancreatic cancer treatment despite negative NICE decision

NICE (the National Institute for Health and Care Excellence) issued its Final Appraisal Determination (FAD) on Abraxane┬« (paclitaxel formulated as albumin bound nanoparticles; nab-paclitaxel) in combination with gemcitabine, and has not recommended it for use by NHS England for the treatment of metastatic adenocarcinoma of the pancreas.[i] In addition, an NHS England review of 42 cancer treatments currently available through the Cancer Drugs Fund (CDF) could result in Abraxane┬« being […]

breast: UTSW study links deficiency of cellular housekeeping gene with aggressive forms of breast cancer

UT Southwestern Medical Center scientists have identified a strong link between the most aggressive type of breast cancer[1] and a gene that regulates the body’s natural cellular recycling process, called autophagy. Based on analysis of two large breast cancer databases, reduced activity of an autophagy gene, beclin 1, was related to both a higher incidence of triple-negative breast cancer and a poorer prognosis for breast cancer patients. The study, published […]

breast: Moffitt study find loss of certain protein is associated with poor prognosis in breast, lung cancer

Study shows a tristetraprolin gene network is common to many different tumors Moffitt Cancer Center researchers have found that breast and lung cancer[1] patients who have low levels of a protein called tristetraprolin (TTP) have more aggressive tumors and a poorer prognosis than those with high levels of the protein. Their study was published recently in PLoS One. Cancer[2] arises through the increased activity of oncogenes, proteins that drive cancer […]

lung: Death rates from lung cancer will overtake those for breast cancer in 2015 among EU women

Death rates from lung cancer[1] will exceed those for breast cancer[2] for the first time among European women in 2015, according to the latest predictions published in the leading cancer[3] journal Annals of Oncology1. The study by researchers in Italy and Switzerland predicts that although the actual number of deaths from all cancers in the European Union will continue to rise due to growing populations and numbers of elderly people, […]

breast: Health systems explore how to meet the needs of an increasing number of breast cancer survivors

More women are surviving breast cancer[1] – and living longer – but the number of oncologists has remained steady, leaving a gap in care for many of the over 2.8 million breast cancer survivors in the United States. Health care systems are starting to transition patients to primary care providers (PCPs) for their survivorship care, but only 10 percent of PCPs working in low-income settings reported meeting the recommended guidelines […]